Influence oligoesters marks l-3603-2-12 and l-10002-2-80 on microsomal oxidation hepatocytes and tissue respiration mitochondria in the experimental animals

نویسنده

  • V. I. Zhukov
چکیده

Studying the effects of prolonged exposure of 2 new brands Oligoesters the state of monooxygenase system microsomes of hepatocytes, tissue respiration and oxidative phosphorylation in the mitochondria showed that Oligoesters makes L-3603-2-12 and L-10002-2-80 in dose 1/100 DL50 stimulate hepatocyte microsomal monooxygenase system, lipid peroxidation, which is associated with inhibition of tissue respiration and oxidative phosphorylation are based on the development of molecular membrane pathology.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identification of Intracellular Sources Responsible for Endogenous Reactive Oxygen Species Formation

The endogenous reactive oxygen species ("ROS") formation is associated with many pathologic states such as inflammatory diseases, neurodegenerative diseases, brain and heart ischemic injuries, cancer, and aging. The purpose of this study was to investigate the endogenous sources for "ROS" formation in intact isolated rat hepatocytes, in particular, peroxisomal oxidases, monoamine oxidase, xanth...

متن کامل

Identification of Intracellular Sources Responsible for Endogenous Reactive Oxygen Species Formation

The endogenous reactive oxygen species ("ROS") formation is associated with many pathologic states such as inflammatory diseases, neurodegenerative diseases, brain and heart ischemic injuries, cancer, and aging. The purpose of this study was to investigate the endogenous sources for "ROS" formation in intact isolated rat hepatocytes, in particular, peroxisomal oxidases, monoamine oxidase, xanth...

متن کامل

Influence of 1-aminoethoxyvinylglycine hydrochloride and α-naphthalene acetic acid on fruit retention, quality, evolved ethylene, and respiration in apples

Effects of 1-aminoethoxyvinylglycine hydrochloride (AVG or Aviglycine HCl or ReTain) and α-naphthalene acetic acid (NAA) on fruit retention, fruit quality, eveloved ethylene, and respiration in ‘Rome Beauty’ and three ‘Delicious’ apple cultivars (Malus domestica Borkh.) were studied.  The experimental trees were treated with either AVG, applied at 120 g a.i. per 935 L. ha-1 or NAA, applied at t...

متن کامل

RESPIRATION AND MITOCHONDRIAL CONTENT IN SINGLE NEURONS OF THE SUPRAOPTIC NUCLEUS A Correlative Study in Osmotic Stress

The study was undertaken to investigate the possible correlation of total volume of mitochondria per cell with the rate of succinate oxidation in isolated nerve cell bodies, after various functional stresses in the experimental animals. Significant cytological effects were found in the nerve cells of the supraoptic nucleus in rats which had been thirsting for 4-12 days or had been given 2% sodi...

متن کامل

Respiration and Mitochondrial Content in Single Neurons of the Supraoptic Nucleus

The study was undertaken to investigate the possible correlation of total volume of mitochondria per cell with the rate of succinate oxidation in isolated nerve cell bodies, after various functional stresses in the experimental animals. Significant cytological effects were found in the nerve cells of the supraoptic nucleus in rats which had been thirsting for 4-12 days or had been given 2% sodi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017